JWH · Class II · 21 CFR 888.3560

FDA Product Code JWH: Prosthesis, Knee, Patellofemorotibial, Semi-constrained, Cemented, Polymer/metal/polymer

Total knee replacement is one of the most common orthopedic procedures in the United States. FDA product code JWH covers semi-constrained patellofemorotibial knee prostheses — implants that replace the articular surfaces of the femur, tibia, and patella to restore pain-free mobility.

These systems are designed to replicate the biomechanics of the natural knee while providing long-term stability. They are used in patients with advanced osteoarthritis, rheumatoid arthritis, or post-traumatic joint damage.

JWH devices are Class II medical devices, regulated under 21 CFR 888.3560 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include Conformis, Inc., Smith & Nephew, Inc. and Maxx Orthopedics, Inc..

71
Total
71
Cleared
68d
Avg days
2021
Since

List of Prosthesis, Knee, Patellofemorotibial, Semi-constrained, Cemented, Polymer/metal/polymer devices cleared through 510(k)

71 devices
1–24 of 71
Cleared Jan 06, 2026
Materialise TKA Guide System
K253793
Materialise NV
Orthopedic · 39d
Cleared Dec 19, 2025
EMPOWR Knee
K252974
Encore Medical, L.P.
Orthopedic · 93d
Cleared Nov 19, 2025
ATTUNE™ Total Knee System
K253197
Depuy Ireland UC
Orthopedic · 54d
Cleared Oct 29, 2025
Freedom Infinia™ Total Knee System
K253314
Maxx Orthopedics, Inc.
Orthopedic · 29d
Cleared Oct 22, 2025
Freedom® Total Knee System – Titan PCK Components
K253144
Maxx Orthopedics, Inc.
Orthopedic · 27d
Cleared Sep 25, 2025
Stem Extension Line (U2 Total Knee System—PSA Type)
K252725
United Orthopedic Corporation
Orthopedic · 28d
Cleared Jul 14, 2025
Materialise TKA Guide System
K251554
Materialise NV
Orthopedic · 54d
Cleared Jul 08, 2025
EMPOWR Revision Knee™ (EMPOWR Revision VVC+, e+ Tibial Insert)
K251776
Encore Medical, L.P.
Orthopedic · 28d
Cleared Jul 02, 2025
EMPOWR Revision Knee™ (EMPOWR Revision Knee™ Symmetric TT Cones)
K251241
Encore Medical, L.P.
Orthopedic · 71d
Cleared Jun 26, 2025
Freedom® Total Knee System – Titanium Tibial Base Plate
K251717
Maxx Orthopedics, Inc.
Orthopedic · 22d
Cleared Apr 17, 2025
EXULT Knee Replacement System
K250889
Corentec Co., Ltd.
Orthopedic · 23d
Cleared Apr 02, 2025
LEGION Total Knee System
K250677
Smith & Nephew, Inc.
Orthopedic · 27d
Cleared Mar 13, 2025
Freedom Total Knee System (All-poly Tibial Plate)
K250382
Maxx Orthopedics, Inc.
Orthopedic · 30d
Cleared Mar 06, 2025
Persona® Revision Knee System (Persona Revision SoluTion™ Femoral Components)
K243724
Zimmer, Inc.
Orthopedic · 93d
Cleared Feb 18, 2025
Evolution® Total Knee Systems - Kinematic Alignment Instrumentation and Technique
K243574
Microport Orthopedics, Inc.
Orthopedic · 91d
Cleared Feb 06, 2025
Scorpio Universal Dome Patella
K243817
Howmedica Osteonics Corp., Dba Stryker Orthopaedics
Orthopedic · 56d
Cleared Dec 20, 2024
Cellbrick Knee Spacer
K243024
United Orthopedic Corporation
Orthopedic · 84d
Cleared Dec 04, 2024
Triathlon Knee System
K242831
Howmedica Osteonics Corp., Dba Stryker Orthopaedics
Orthopedic · 76d
Cleared Nov 19, 2024
Freedom® Medial Congruent Liner
K243277
Maxx Orthopedics, Inc.
Orthopedic · 34d
Cleared Oct 25, 2024
BKS Revision System
K242984
Ortho Development Corp.
Orthopedic · 29d
Cleared Sep 23, 2024
Unity Total Knee System
K241570
Corin U.S.A. Limited
Orthopedic · 115d
Cleared Sep 12, 2024
EXULT Knee Replacement System
K242401
Corentec Co., Ltd.
Orthopedic · 30d
Cleared Sep 11, 2024
Rx Knee System
K240683
Signature Orthopaedics Pty, Ltd.
Orthopedic · 183d
Cleared Aug 01, 2024
EXULT Knee Replacement System
K242046
Corentec Co., Ltd.
Orthopedic · 20d

How to use this database

This page lists all FDA 510(k) submissions for Prosthesis, Knee, Patellofemorotibial, Semi-constrained, Cemented, Polymer/metal/polymer devices (product code JWH). Click any device to view full submission details, including the decision date, manufacturer information, predicate device, and a link to the official FDA record.

These devices fall under the Orthopedic FDA review panel. Browse all Orthopedic devices →