Cleared Traditional

TIGR Matrix Surgical Mesh, TIGR Surgical Mesh (K191749) - FDA 510(k) Clearance

Class II General & Plastic Surgery device cleared through predicate-based substantial equivalence.

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Mar 2020
Decision
269d
Days
Class 2
Risk

K191749 is an FDA 510(k) clearance for the TIGR Matrix Surgical Mesh, TIGR Surgical Mesh. Classified as Mesh, Surgical, Absorbable, Abdominal Hernia (product code OWT), Class II - Special Controls.

Submitted by Novus Scientific AB (Uppsala, SE). The FDA issued a Cleared decision on March 26, 2020 after a review of 269 days - an extended review cycle.

This device falls under the General & Plastic Surgery FDA review panel, regulated under 21 CFR 878.3300 - the FDA general and plastic surgery device framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the General & Plastic Surgery review framework, consistent with the majority of Class II 510(k) submissions.

View all Novus Scientific AB devices

Submission Details

510(k) Number K191749 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received July 01, 2019
Decision Date March 26, 2020
Days to Decision 269 days
Submission Type Traditional
Review Panel General & Plastic Surgery (SU)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
154d slower than avg
Panel avg: 115d · This submission: 269d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code OWT Mesh, Surgical, Absorbable, Abdominal Hernia
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 878.3300
Definition For Reinforcement Of Soft Tissue Where Weakness Exists During Hernia Repair.
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most General & Plastic Surgery devices follow this clearance model.

Regulatory Consultant

Cygnus Regulatory, LLC
Loredana M Guseila

The regulatory consultant manages the 510(k) submission process on behalf of the applicant - coordinating technical documentation, predicate strategy and FDA communications. Identifying the consultant behind a submission is a key signal for competitive regulatory intelligence.

Clinical Evidence

ClinicalTrials.gov
NCT01622725 Completed Interventional

Primary and Secondary Ventral Hernia Repair Using Long-term Resorbable Versus Non-resorbable Large Pore Synthetic Mesh.

Recurrence Rate After Primary and Secondary Ventral Hernia Repair Using Long-term Resorbable Versus Non-resorbable Large Pore Synthetic Mesh.

95
Patients (actual)
6
Sites
Treatment
Purpose
Double blind
Masking
Condition studied Primary and Secondary Ventral Hernia
Study design Parallel
Eligibility All sexes · 18 Years+
Principal investigator Frederik Berrevoet, MD, PhD
Sponsor University Hospital, Ghent
Started 2013-02-01 Primary completion 2021-08-01 Completed 2023-12-31
Primary outcome
Recurrence rate at 3 years post-surgery.
Secondary outcome
Wound Morbidity 4 weeks post-surgery.
Study completed - no results published. This trial concluded in 2023 but has not posted results to ClinicalTrials.gov. Completed studies without public results are common in industry-sponsored device trials; the data may be referenced in the 510(k) Summary PDF or remain unpublished.
View full study on ClinicalTrials.gov

Regulatory Peers - OWT Mesh, Surgical, Absorbable, Abdominal Hernia

All 10
Devices cleared under the same product code (OWT) and FDA review panel - the closest regulatory comparables to K191749.
Phasix ST Umbilical Hernia Patch
K243241 · Davol, Inc., A Subsidiary of C.R. Bard, Inc. · Feb 2025
Transorb™ Self-Gripping Resorbable Mesh
K233661 · Sofradim Production · Feb 2024
GORE BIO-A Tissue Reinforcement
K191773 · W.L. Gore & Associates, Inc. · Jul 2019
Phasix ST Mesh with Open Positioning System
K190185 · C.R. Bard, Inc. · Jun 2019
Phasix ST Mesh
K173143 · C.R. Bard, Inc. · Apr 2018
Phasix ST Mesh
K143380 · C.R. Bard, Inc. · Jun 2015