OVE · Class II · 21 CFR 888.3080

FDA Product Code OVE: Intervertebral Fusion Device With Integrated Fixation, Cervical

FDA product code OVE covers cervical intervertebral fusion devices with integrated fixation.

These single-piece implants combine an interbody spacer with integrated anterior fixation screws or blades, providing both disc space support and vertebral stabilization without a separate plate. They are used in one- or two-level anterior cervical discectomy and fusion procedures.

OVE devices are Class II medical devices, regulated under 21 CFR 888.3080 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include SeaSpine Orthopedics Corporation, Genesys Spine and Signus Medizintechnik GmbH.

15
Total
15
Cleared
117d
Avg days
2021
Since

List of Intervertebral Fusion Device With Integrated Fixation, Cervical devices cleared through 510(k)

15 devices
1–15 of 15
Cleared Dec 22, 2025
HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer)
K253876
Globus Medical, Inc.
Orthopedic · 18d
Cleared Jun 27, 2025
FIX-C PEEK ACIF SA System
K251431
Jeil Medical Corporation
Orthopedic · 50d
Cleared Feb 11, 2025
CYLOX® ST
K243188
Signus Medizintechnik GmbH
Orthopedic · 134d
Cleared Feb 07, 2025
Genesys Spine AIS-C II Cervical Interbody Fusion System
K242483
Genesys Spine
Orthopedic · 170d
Cleared Dec 13, 2023
Genesys Spine 3DP AIS-C II Cervical Interbody System
K233594
Genesys Spine
Orthopedic · 35d
Cleared Nov 28, 2023
Shoreline ACS Interbody System
K233414
SeaSpine Orthopedics Corporation
Orthopedic · 49d
Cleared Oct 27, 2023
RIGEL™ 3DR Standalone Anterior Cervical Interbody Fusion System
K232348
MiRus, LLC
Orthopedic · 81d
Cleared Oct 19, 2023
Pro-Link® & Pro-Link® Ti Barbs Cervical Spacer System
K231704
Life Spine, Inc.
Orthopedic · 129d
Cleared Aug 12, 2022
Zavation VariSync Plate System and VariSync Spacer System
K221049
Zavation Medical Products, LLC
Orthopedic · 123d
Cleared Feb 04, 2022
F3D-C2 Cervical Stand-Alone System
K211417
Corelink, LLC
Orthopedic · 273d
Cleared Dec 14, 2021
SeaSpine WaveForm C Interbody System
K212904
SeaSpine Orthopedics Corporation
Orthopedic · 92d
Cleared Dec 09, 2021
SeaSpine WaveForm, C Interbody System
K213359
SeaSpine Orthopedics Corporation
Orthopedic · 58d
Cleared Nov 19, 2021
Velofix SA Cervical Cage
K210573
U&I Corporation
Orthopedic · 266d
Cleared Sep 03, 2021
C-CURVE Interbody Fusion Device
K210470
Medicrea International SA
Orthopedic · 198d
Cleared Jan 12, 2021
NexGen Standalone Anterior Cervical Discectomy and Fusion (ACDF) System
K203129
Precision Spine, Inc.
Orthopedic · 85d

How to use this database

This page lists all FDA 510(k) submissions for Intervertebral Fusion Device With Integrated Fixation, Cervical devices (product code OVE). Click any device to view full submission details, including the decision date, manufacturer information, predicate device, and a link to the official FDA record.

These devices fall under the Orthopedic FDA review panel. Browse all Orthopedic devices →