QHE · Class II · 21 CFR 888.3660

FDA Product Code QHE: Shoulder Arthroplasty Implantation System

Precise component placement is critical to the outcomes of shoulder replacement surgery. FDA product code QHE covers shoulder arthroplasty implantation systems — instrumented systems designed to assist surgeons in accurately preparing the bone and seating the prosthetic components.

These systems include patient-specific guides, navigation tools, and mechanical jigs that improve the accuracy of glenoid and humeral preparation, potentially reducing the risk of implant malposition and early failure.

QHE devices are Class II medical devices, regulated under 21 CFR 888.3660 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include Materialise NV, Arthrex, Inc. and Precision AI Pty, Ltd..

24
Total
24
Cleared
120d
Avg days
2019
Since
Stable submission activity - 9 submissions in the last 2 years
Review times increasing: avg 132d recently vs 113d historically

FDA 510(k) Cleared Shoulder Arthroplasty Implantation System Devices (Product Code QHE)

24 devices
1–24 of 24
Cleared Feb 04, 2026
Signature™ ONE System
K260104
Orthosoft Inc. (d/b/a) Zimmer CAS
Orthopedic · 22d
Cleared Jan 12, 2026
Precision AI Surgical Planning System (PAI-SPS)
K251558
Precision AI Pty, Ltd.
Orthopedic · 236d
Cleared May 12, 2025
Archer PSI System
K243509
3D-Side
Orthopedic · 181d
Cleared Feb 20, 2025
CORE Shoulder System
K241470
LinkBio Corp.
Orthopedic · 272d
Cleared Jan 21, 2025
Precision AI Surgical Planning System (PAI-SPS)
K243955
Precision AI Pty, Ltd.
Orthopedic · 29d
Cleared Oct 18, 2024
Materialise Shoulder System™, Materialise Shoulder Guide and Models, SurgiCase Shoulder Planner
K242813
Materialise NV
Orthopedic · 30d
Cleared Oct 02, 2024
Arthrex Virtual Implant Positioning (VIP) System Software
K241097
Arthrex, Inc.
Orthopedic · 163d
Cleared Aug 05, 2024
Precision AI Surgical Planning System (PAI-SPS)
K233992
Precision AI Pty, Ltd.
Orthopedic · 231d
Cleared May 22, 2024
Materialise Shoulder System™, Materialise Shoulder Guide and Models, SurgiCase Shoulder Planner
K241143
Materialise NV
Orthopedic · 27d
Cleared Dec 12, 2023
Signature™ ONE System
K232425
Orthosoft Inc. (d/b/a) Zimmer CAS
Orthopedic · 123d
Cleared Nov 09, 2023
Materialise Shoulder System™, Materialise Shoulder Guide and Models, SurgiCase Shoulder Planner
K233408
Materialise NV
Orthopedic · 34d
Cleared Sep 12, 2023
Materialise Shoulder System™, Materialise Shoulder Guide and Models, SurgiCase Shoulder Planner
K231112
Materialise NV
Orthopedic · 146d
Cleared Jun 22, 2023
Arthrex Virtual Implant Positioning (VIP) System
K230904
Arthrex, Inc.
Orthopedic · 83d
Cleared Mar 08, 2023
Arthrex Virtual Implant Positioning (VIP) System
K222007
Arthrex, Inc.
Orthopedic · 244d
Cleared Mar 06, 2023
Materialise Shoulder System™ Materialise Shoulder Guide and Models SurgiCase Shoulder Planner
K230315
Materialise NV
Orthopedic · 28d
Cleared Dec 20, 2022
Smart SPACE Shoulder Planner and 3D Positioners
K222405
Lima Corporate S.P.A.
Orthopedic · 133d
Cleared Aug 17, 2022
Materialise Shoulder SystemTM Materialise Shoulder Guide and Models SurgiCase Shoulder Planner
K220452
Materialise NV
Orthopedic · 181d
Cleared Jan 12, 2022
Materialise Shoulder System™, Materialise Shoulder Guide and Models, SurgiCase Shoulder Planner
K212569
Materialise NV
Orthopedic · 149d

About Product Code QHE - Regulatory Context

510(k) Submission Activity

24 total 510(k) submissions under product code QHE since 2019, with 24 receiving FDA clearance (average review time: 120 days).

Submission volume has remained relatively stable over the observed period, with 9 submissions in the last 24 months.

FDA Review Time

Recent submissions under QHE have taken an average of 132 days to reach a decision - up from 113 days historically. Manufacturers should account for longer review timelines in current project planning.

QHE devices are reviewed by the Orthopedic panel. Browse all Orthopedic devices →