BTT · Class II · 21 CFR 868.5450

FDA Product Code BTT: Humidifier, Respiratory Gas, (direct Patient Interface)

Delivering humidified gas to mechanically ventilated patients prevents airway desiccation and protects mucosal integrity. FDA product code BTT covers direct patient interface respiratory gas humidifiers.

These devices add heat and moisture to inspired gases delivered through ventilator circuits or oxygen therapy systems, maintaining physiological humidity levels in the airways. They are essential in neonatal intensive care and long-term ventilator-dependent patients.

BTT devices are Class II medical devices, regulated under 21 CFR 868.5450 and reviewed by the FDA Anesthesiology panel.

Leading manufacturers include Fisher &Paykel Healthcare , Ltd., Medline Industries, LP and Laboratorios Biogalenic S.A. DE C.V..

221
Total
221
Cleared
151d
Avg days
1976
Since
Stable submission activity - 12 submissions in the last 2 years
Consistent review times: 172d avg (recent)

FDA 510(k) Cleared Humidifier, Respiratory Gas, (direct Patient Interface) Devices (Product Code BTT)

221 devices
1–24 of 221
Cleared Apr 13, 2026
HVT 2.0
K254078
Vapotherm, Inc.
Anesthesiology · 116d
Cleared Jan 16, 2026
FL-10000U Respiratory Humidifier
K251448
Flexicare Medical Limited.
Anesthesiology · 252d
Cleared Jan 14, 2026
Laboratorios Biogalenic Sterile Water for Inhalation, USP
K251419
Laboratorios Biogalenic S.A. DE C.V.
Anesthesiology · 252d
Cleared Dec 19, 2025
Optiflow Switch+ Filtered Nasal Interface with CO2 Sampling (AA042J)
K253479
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 66d
Cleared Jul 02, 2025
Hudson RCI® Comfort Flo Nasal Cannula Premature, Infant
K250312
Medline Industries, LP
Anesthesiology · 149d
Cleared Jun 25, 2025
Optiflow+ Nasal Cannula - Small (OPT942)
K251611
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 29d
Cleared Jan 30, 2025
Laboratorios Biogalenic Sterile Water for Inhalation, USP
K242717
Laboratorios Biogalenic S.A. DE C.V.
Anesthesiology · 142d
Cleared Dec 19, 2024
Hudson RCI Comfort Flo® CubCannula™
K241778
Medline Industries, LP
Anesthesiology · 182d
Cleared Sep 27, 2024
Hudson RCI® Comfort Flo Nasal Cannula
K240163
Medline Industries, LP
Anesthesiology · 249d
Cleared Aug 08, 2024
F&P Optiflow Filtered Nasal Interface with Anesthesia Mask Compatibility (AA041J)
K234058
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 230d
Cleared Jun 14, 2024
HFT150
K233707
Invent Medical Corporation
Anesthesiology · 207d
Cleared Jun 13, 2024
F&P Optiflow Oxygen Kit (AA451J)
K233821
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 195d
Cleared May 08, 2024
F&P myAirvo 3
K222292
Fisher & Paykel Healthcare
Anesthesiology · 649d
Cleared Feb 07, 2024
F&P Optiflow+ Duet Nasal Cannula
K231956
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 219d
Cleared Oct 26, 2023
Hudson RCI® Disposable Humidifier with 4 PSI Pressure Relief Valve (3230), Hudson RCI® Disposable Humidifier with 6 PSI Pressure Relief Valve (3260)
K230559
Medline Industries, Inc.
Anesthesiology · 240d
Cleared Sep 05, 2023
F&P 820 Humidification System
K223684
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 271d
Cleared Apr 06, 2023
F&P Optiflow Junior 2/2+ Nasal Cannula Interface Range
K222197
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 258d
Cleared Apr 22, 2022
F&P 850 AirSpiral Adult NIV and NHF Circuit Kit
K212031
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 297d
Cleared Jan 28, 2022
Optiflow Oxygen Kit
K211096
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 290d
Cleared Mar 16, 2021
F&P Optiflow Nasal Oxygen Cannula with CO2 Sampling
K201723
Fisher &Paykel Healthcare , Ltd.
Anesthesiology · 266d

About Product Code BTT - Regulatory Context

510(k) Submission Activity

221 total 510(k) submissions under product code BTT since 1976, with 221 receiving FDA clearance (average review time: 151 days).

Submission volume has remained relatively stable over the observed period, with 12 submissions in the last 24 months.

FDA Review Time

FDA review times for BTT submissions have been consistent, averaging 172 days recently vs 150 days historically.

BTT devices are reviewed by the Anesthesiology panel. Browse all Anesthesiology devices →