DTZ · Class II · 21 CFR 870.4350

FDA Product Code DTZ: Oxygenator, Cardiopulmonary Bypass

The heart-lung machine depends on a reliable oxygenator to sustain patients during open-heart surgery. FDA product code DTZ covers cardiopulmonary bypass oxygenators.

These devices perform gas exchange outside the body — adding oxygen and removing carbon dioxide from venous blood during cardiopulmonary bypass, temporarily replacing the function of the lungs. Modern hollow-fiber membrane oxygenators minimize blood trauma and reduce post-operative complications.

DTZ devices are Class II medical devices, regulated under 21 CFR 870.4350 and reviewed by the FDA Cardiovascular panel.

Leading manufacturers include Sorin Group Italia S.R.L., Medtronic, Inc. and Qura S.R.L.

254
Total
254
Cleared
134d
Avg days
1976
Since
Stable submission activity - 7 submissions in the last 2 years
Review times increasing: avg 304d recently vs 129d historically

FDA 510(k) Cleared Oxygenator, Cardiopulmonary Bypass Devices (Product Code DTZ)

254 devices
1–24 of 254
Cleared Mar 16, 2026
Lifemotion Disposable Membrane Oxygenator
K253838
Lifemotion Medical Technology Co., Ltd.
Cardiovascular · 105d
Cleared Mar 12, 2026
Quantum Perfusion Blood Oxygenator ECC VT160-E3 (VT160-E3)
K240934
Spectrum Medical S.R.L.
Cardiovascular · 706d
Cleared Dec 12, 2025
Horizon AF Plus System (Integrated A.L. One AF Plus OXYGENATOR and Horizon CVR) (US5300)
K250821
Eurosets S.R.L
Cardiovascular · 269d
Cleared Nov 24, 2025
Trilly Pediatric Oxygenator with Integrated Arterial Filter (US5232)
K242503
Eurosets S.R.L
Cardiovascular · 459d
Cleared Sep 12, 2024
Quantum Perfusion Blood Oxygenator VT75-E1, Quantum Perfusion Blood Oxygenator VT75-E2
K231982
Qura S.R.L
Cardiovascular · 435d
Cleared Jul 10, 2024
Affinity Fusion Oxygenator with Integrated Arterial Filter and Balance Biosurface (BB811)
K240666
Medtronic Perfusion Systems
Cardiovascular · 124d
Cleared Jun 12, 2024
Affinity NT Oxygenator and Uncoated Cardiotomy/ Venous Reservoir (541)
K241352
Medtronic, Inc.
Cardiovascular · 30d
Cleared Nov 16, 2023
D100 KIDS
K231652
Sorin Group Italia S.R.L.
Cardiovascular · 163d
Cleared Nov 08, 2023
Quantum Perfusion Blood Oxygenator with Integrated AF and Sensor VT75-C1U, Quantum Perfusion Blood Oxygenator with Integrated AF VT75-C2U, Quantum Perfusion Blood Oxygenator with Integrated AF and Sensor VT200-C1U, Quantum Perfusion Blood Oxygenator with Integrated AF VT200-C2U, Quantum Perfusion Blood Oxygenator with Integrated AF and Sensor VT160-C1U
K231773
Qura S.R.L
Cardiovascular · 145d
Cleared Apr 06, 2023
Affinity Fusion™ Oxygenator System
K230640
Medtronic, Inc.
Cardiovascular · 29d
Cleared Feb 23, 2023
OXY-1 System
K223161
Abiomed, Inc.
Cardiovascular · 139d
Cleared Sep 16, 2021
Affinity Fusion Oxygenator System, Affinity Pixie Oxygenation System
K203111
Medtronic
Cardiovascular · 336d
Cleared Jul 12, 2021
EOS PMP
K211495
Sorin Group Italia S.R.L.
Cardiovascular · 60d

About Product Code DTZ - Regulatory Context

510(k) Submission Activity

254 total 510(k) submissions under product code DTZ since 1976, with 254 receiving FDA clearance (average review time: 134 days).

Submission volume has remained relatively stable over the observed period, with 7 submissions in the last 24 months.

FDA Review Time

Recent submissions under DTZ have taken an average of 304 days to reach a decision - up from 129 days historically. Manufacturers should account for longer review timelines in current project planning.

DTZ devices are reviewed by the Cardiovascular panel. Browse all Cardiovascular devices →