FRC · Class II · 21 CFR 880.2800

FDA Product Code FRC: Indicator, Biological Sterilization Process

Ensuring the effectiveness of sterilization cycles is a patient safety requirement in every healthcare setting. FDA product code FRC covers biological sterilization process indicators.

These indicators contain highly resistant bacterial spores that are killed only if the sterilization cycle achieves the required parameters. They provide the most stringent validation of steam, EO, or other sterilization processes, and their use is mandated by accreditation standards.

FRC devices are Class II medical devices, regulated under 21 CFR 880.2800 and reviewed by the FDA General Hospital panel.

Leading manufacturers include 3M Company, STERIS Corporation and Steris.

206
Total
206
Cleared
169d
Avg days
1977
Since
Growing category - 14 submissions in the last 2 years vs 9 in the prior period
Review times improving: avg 97d recently vs 174d historically

FDA 510(k) Cleared Indicator, Biological Sterilization Process Devices (Product Code FRC)

206 devices
1–24 of 206
Cleared Apr 08, 2026
Celerity 5 HP Biological Indicator (LCB052)
K260766
STERIS Corporation
General Hospital · 30d
Cleared Sep 24, 2025
Celerity™ 20 HP Biological Indicator
K252680
STERIS Corporation
General Hospital · 30d
Cleared Aug 04, 2025
Terragene® Bionova® BT20 Biological Indicator
K251122
Terragene
General Hospital · 115d
Cleared Jun 06, 2025
Celerity 5 HP Biological Indicator (LCB052)
K251452
Steris
General Hospital · 28d
Cleared Feb 06, 2025
Celerity 5 HP Biological Indicator (LCB052)
K250044
STERIS Corporation
General Hospital · 27d
Cleared Feb 06, 2025
Celerity Incubator
K250061
STERIS Corporation
General Hospital · 27d
Cleared Jan 28, 2025
3M™ Attest™ Super Rapid Steam Extended Cycle Clear Challenge Pack 1492PCDE
K243501
3M Company
General Hospital · 77d
Cleared Dec 12, 2024
Terragene® Bionova® Photon Process Challenge Device with unique-point integrator (PCD225-2)
K242453
Terragene S.A.
General Hospital · 115d
Cleared Nov 25, 2024
3M™ Attest™ Super Rapid Readout Biological Indicator 1493
K242538
3M Company
General Hospital · 91d
Cleared Oct 18, 2024
3M™ Attest™ Super Rapid Steam Clear Challenge Pack (1492PCD)
K241959
3M Company
General Hospital · 107d
Cleared Sep 18, 2024
Terragene® Bionova® Self-Contained Biological Indicator (BT95), Terragene® Bionova® Self-Contained Biological Indicator (BT96), Terragene® Chemdye® Chemical Process Indicator (CD42), Terragene® Cintape® Chemical Process Indicator Tape (CT40)
K231383
Terragene S.A.
General Hospital · 495d
Cleared Sep 12, 2024
3M™ Attest™ Super Rapid Readout Biological Indicator 1492V
K241710
3M Company
General Hospital · 90d
Cleared Jun 27, 2024
3M™ Attest™ Rapid Readout Biological Indicator 1295 and 3M™ Attest™ Vaporized Hydrogen Peroxide Tri-Metric Chemical Indicator 1348/1348E
K240717
3M Company
General Hospital · 104d
Cleared Jun 27, 2024
3M™ Attest™ Super Rapid Vaporized Hydrogen Peroxide Clear Challenge Pack 1295PCD (1295PCD)
K241542
3M Company
General Hospital · 27d
Cleared Mar 15, 2024
3M™ Attest™ Super Rapid Vaporized Hydrogen Peroxide Clear Challenge Pack (1295PCD)
K233814
3M Company
General Hospital · 106d
Cleared Dec 15, 2023
ConFirm 20 Minute Incubator
K233681
STERIS Corporation
General Hospital · 29d
Cleared Aug 07, 2023
Celerity 20 HP Biological Indicator
K231490
STERIS Corporation
General Hospital · 76d
Cleared Jun 15, 2023
Celerity Incubator
K223715
STERIS Corporation
General Hospital · 195d
Cleared Jun 15, 2023
Celerity 5 HP Biological Indicator
K223717
STERIS Corporation
General Hospital · 185d
Cleared Jul 21, 2022
Celerity Incubator
K213881
STERIS Corporation
General Hospital · 220d
Cleared Jun 28, 2022
3M Attest Rapid Readout Biological Indicator, 1295
K211705
3M Company
General Hospital · 390d
Cleared Apr 06, 2022
3M Attest Super Rapid Steam Biological Indicator, 3M Attest Super Rapid Steam Challenge Pack, 3M Attest Auto-reader, 3M Attest Mini Auto-reader
K213809
3M Company
General Hospital · 121d
Cleared Mar 18, 2022
CELERITY 20 HP Challenge Pack
K220473
Steris
General Hospital · 28d
Cleared Mar 03, 2021
3M Attest Rapid Readout Biological Indicator, 1295
K210277
3M Company
General Hospital · 30d

About Product Code FRC - Regulatory Context

510(k) Submission Activity

206 total 510(k) submissions under product code FRC since 1977, with 206 receiving FDA clearance (average review time: 169 days).

Submission volume has increased in recent years - 14 submissions in the last 24 months compared to 9 in the prior period - suggesting growing market activity in this device classification.

FDA Review Time

Recent submissions under FRC have taken an average of 97 days to reach a decision - down from 174 days historically, suggesting improved FDA processing for this classification.

FRC devices are reviewed by the General Hospital panel. Browse all General Hospital devices →