GKZ · Class II · 21 CFR 864.5220

FDA Product Code GKZ: Counter, Differential Cell

FDA product code GKZ covers differential cell counters used in hematology laboratories.

These automated or semi-automated instruments classify and count white blood cell subtypes — neutrophils, lymphocytes, monocytes, eosinophils, and basophils — from blood smears or liquid samples. The differential count is a critical component of the complete blood count used to diagnose infections, hematological disorders, and immune conditions.

GKZ devices are Class II medical devices, regulated under 21 CFR 864.5220 and reviewed by the FDA Hematology panel.

Leading manufacturers include Sysmex America, Inc., Abbott Laboratories and Beckman Coulter, Inc..

379
Total
379
Cleared
173d
Avg days
1977
Since
Growing category - 8 submissions in the last 2 years vs 6 in the prior period
Review times increasing: avg 221d recently vs 172d historically

FDA 510(k) Cleared Counter, Differential Cell Devices (Product Code GKZ)

379 devices
1–24 of 379
Cleared Feb 06, 2026
Athelas Home
K243348
Athelas, Inc.
Hematology · 466d
Cleared Jan 16, 2026
Tru Hematology Test
K251249
Truvian Sciences, Inc.
Hematology · 268d
Cleared Jun 25, 2025
Sysmex XR-Series (XR-10) Automated Hematology Analyzer
K250943
Sysmex America, Inc.
Hematology · 89d
Cleared Jun 25, 2025
Sysmex XR-Series (XR-20) Automated Hematology Analyzer
K251371
Sysmex America, Inc.
Hematology · 54d
Cleared Feb 20, 2025
Alinity h-series System
K243283
Abbott Laboratories
Hematology · 126d
Cleared Feb 03, 2025
Cito CBC System
K240402
Cytochip, Inc.
Hematology · 360d
Cleared Jul 05, 2024
UniCel DxH 900 Coulter Cellular Analysis System
K240252
Beckman Coulter, Inc.
Hematology · 157d
Cleared May 21, 2024
Yumizen H2500
K232946
HORIBA ABX SAS
Hematology · 244d
Cleared May 02, 2024
HemoScreen Hematology Analyzer
K240636
Pixcell Medical Technologies
Hematology · 57d
Cleared Dec 21, 2023
Sysmex XQ-Series (XQ-320) Automated Hematology Analyzer
K230887
Sysmex America, Inc.
Hematology · 265d
Cleared Aug 04, 2023
Alinity h-series System
K220031
Abbott Laboratories
Hematology · 576d
Cleared Nov 08, 2022
Sysmex XW-100 Automated Hematology Analyzer
K210346
Sysmex America, Inc.
Hematology · 638d
Cleared Mar 15, 2019
CELL-DYN Emerald 22 AL System
K190294
Abbott Laboratories
Hematology · 32d
Cleared Jan 25, 2019
Sysmex XN-L Automated Hematology Analyzer
K182389
Sysmex America, Inc.
Hematology · 143d
Cleared Nov 06, 2017
XW-100 Automated Hematology Analyzer for CLIA Waived Use
K172604
Sysmex America, Inc.
Hematology · 68d
Cleared Aug 11, 2017
ADVIA 2120i, ADVIA 2120
K162977
Siemens Healthcare Diagnostics
Hematology · 289d
Cleared Dec 22, 2016
Sysmex XN-L Automated Hematology Analyzer
K160538
Sysmex America, Inc.
Hematology · 300d
Cleared Nov 29, 2016
UniCel DxH SlideMaker Stainer Coulter Cellular Analysis System
K162414
Beckman Coulter, Inc.
Hematology · 92d
Cleared Oct 12, 2015
XW-100 Automated Hematology Analyzer, XW QC CHECK
K143577
Sysmex America, Inc.
Hematology · 299d

About Product Code GKZ - Regulatory Context

510(k) Submission Activity

379 total 510(k) submissions under product code GKZ since 1977, with 379 receiving FDA clearance (average review time: 173 days).

Submission volume has increased in recent years - 8 submissions in the last 24 months compared to 6 in the prior period - suggesting growing market activity in this device classification.

FDA Review Time

Recent submissions under GKZ have taken an average of 221 days to reach a decision - up from 172 days historically. Manufacturers should account for longer review timelines in current project planning.

GKZ devices are reviewed by the Hematology panel. Browse all Hematology devices →