Cleared Traditional

K133323 - VOLCANO IFR MODALITY

K133323 is an FDA 510(k) clearance for VOLCANO IFR MODALITY, manufactured by Volcano Corporation. The device is a Class 2 Radiology device with product code IYO cleared through the Traditional 510(k) pathway after a 136-day FDA review.

Download Printable Device Report (PDF)
Optimized for regulatory review, auditing and printing
Mar 2014
Decision
136d
Days
Class 2
Risk

K133323 is an FDA 510(k) clearance for the VOLCANO IFR MODALITY. Classified as System, Imaging, Pulsed Echo, Ultrasonic (product code IYO), Class II - Special Controls.

Submitted by Volcano Corporation (San Diego, US). The FDA issued a Cleared decision on March 14, 2014 after a review of 136 days - within the typical 510(k) review window.

This device falls under the Radiology FDA review panel, regulated under 21 CFR 892.1560 - the FDA radiology and imaging software oversight framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the Radiology review framework, consistent with the majority of Class II 510(k) submissions.

View all Volcano Corporation devices

FDA 510(k) Submission Details - K133323

510(k) Number K133323 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received October 29, 2013
Decision Date March 14, 2014
Days to Decision 136 days
Submission Type Traditional
Review Panel Radiology (RA)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
29d slower than avg
Panel avg: 107d · This submission: 136d
Pathway characteristics
Predicate-based equivalence.

IYO Device Classification - Class 2, Special Controls

Product Code IYO System, Imaging, Pulsed Echo, Ultrasonic
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 892.1560
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most Radiology devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT01740895 Completed Observational Industry-sponsored

ADenosine Vasodilator Independent Stenosis Evaluation II - ADVISE II

A Prospective, Observational, Non-randomized, Double Blind, Global, Multi-center Registry With an Adaptive Design, Investigating the Diagnostic Utility of Instantaneous Wave-free Ratio™ (iFR®) in Assessing Coronary Stenosis Relevance.

818
Patients (actual)
44
Sites
Condition studied Cardiovascular Disease
Eligibility All sexes · 18 Years+
Principal investigator Javier Escaned, MD
Sponsor Volcano Corporation (industry)
Started 2012-12-01 Primary completion 2013-06-01
Primary outcome
Hemodynamic Severity
Secondary outcome
Specificity
Study completed - no results published. This trial concluded in 2013 but has not posted results to ClinicalTrials.gov. Completed studies without public results are common in industry-sponsored device trials; the data may be referenced in the 510(k) Summary PDF or remain unpublished.
View full study on ClinicalTrials.gov

Regulatory Peers - IYO System, Imaging, Pulsed Echo, Ultrasonic

All 431
Devices cleared under the same product code (IYO) and FDA review panel - the closest regulatory comparables to K133323.
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VOLCANO CORE CONTROL PAD, ACCESSORY TO THE VOLCANO S5/S5I INTRAVASCULAR ULTRASOUND IMAGING & PRESSURE SYSTEMS
K140291 · Volcano Corporation · Mar 2014
CORE CONTROL PAD, CORE SERIES SW V3.4 INSTALLATION KIT, CORE, CORE MOBILE
K133641 · Volcano Corporation · Dec 2013
VOLCANO LOMAP,VOLCANO LOMAP OPTION KIT FOR MOBILE SYSTEM,VOLCANO LOMAP OPTION FOR INTEGRATED SYSTEM,VOLCANO S5 PRECISION
K133142 · Volcano Corporation · Nov 2013