Cleared Traditional

K211645 - Epione (FDA 510(k) Clearance)

Class II Radiology device cleared through predicate-based substantial equivalence.

Download Printable Device Report (PDF)
Optimized for regulatory review, auditing and printing
Feb 2022
Decision
272d
Days
Class 2
Risk

K211645 is an FDA 510(k) clearance for the Epione. Classified as System, X-ray, Tomography, Computed (product code JAK), Class II - Special Controls.

Submitted by Quantum Surgical Sas (Montpellier, FR). The FDA issued a Cleared decision on February 24, 2022 after a review of 272 days - an extended review cycle.

This device falls under the Radiology FDA review panel, regulated under 21 CFR 892.1750 - the FDA radiology and imaging software oversight framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the Radiology review framework, consistent with the majority of Class II 510(k) submissions.

View all Quantum Surgical Sas devices

Submission Details

510(k) Number K211645 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received May 28, 2021
Decision Date February 24, 2022
Days to Decision 272 days
Submission Type Traditional
Review Panel Radiology (RA)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
165d slower than avg
Panel avg: 107d · This submission: 272d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code JAK System, X-ray, Tomography, Computed
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 892.1750
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most Radiology devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT04230642 Completed Interventional Industry-sponsored

Multicenter Study to Evaluate a New Robotic Device for Image-guided Percutaneous Needle Placement

Multicenter Study to Evaluate the Safety and Performance of the Quantum Surgical Robotic Device for Image-guided Percutaneous Needle Placement

22
Patients (actual)
2
Sites
Treatment
Purpose
Open label
Masking
Condition studied Hepatic Tumor
Study design Single group
Eligibility All sexes · 18 Months+
Principal investigator Boris Guiu, MD
Sponsor Quantum Surgical (industry)
Started 2020-05-25 Primary completion 2021-02-02
Primary outcome
Evaluation of the safety related to the procedure
Secondary outcome
Evaluation of the accuracy of the device
Study completed - no results published. This trial concluded in 2021 but has not posted results to ClinicalTrials.gov. Completed studies without public results are common in industry-sponsored device trials; the data may be referenced in the 510(k) Summary PDF or remain unpublished. Individual participant data will not be shared.
View full study on ClinicalTrials.gov

Regulatory Peers - JAK System, X-ray, Tomography, Computed

All 816
Devices cleared under the same product code (JAK) and FDA review panel - the closest regulatory comparables to K211645.
Spectral CT Verida Family
K253649 · Philips Medical Systems Technologies , Ltd. · Mar 2026
CT Rembra RT
K252992 · Philips Healthcare (Suzhou) Co., Ltd. · Mar 2026
True Definition DL
K253686 · Ge Healthcare Japan Corporation · Mar 2026
Photonova Spectra, Photonova Spectra Select
K253520 · Ge Medical Systems, LLC · Mar 2026
SOMATOM X.cite
K253574 · Siemens Medical Solutions USA, Inc. · Mar 2026
Extremity CT Imaging System
K252249 · Mars Bioimaging , Ltd. · Mar 2026