Cleared Traditional

K231024 - AquaBeam Robotic System (FDA 510(k) Clearance)

Class II Gastroenterology & Urology device cleared through predicate-based substantial equivalence.

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Aug 2023
Decision
141d
Days
Class 2
Risk

K231024 is an FDA 510(k) clearance for the AquaBeam Robotic System. Classified as Fluid Jet Removal System (product code PZP), Class II - Special Controls.

Submitted by Procept Biorobotics, Corporation (Redwood City, US). The FDA issued a Cleared decision on August 30, 2023 after a review of 141 days - within the typical 510(k) review window.

This device falls under the Gastroenterology & Urology FDA review panel, regulated under 21 CFR 876.4350 - the FDA gastroenterology and urology device framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the Gastroenterology & Urology review framework, consistent with the majority of Class II 510(k) submissions.

View all Procept Biorobotics, Corporation devices

Submission Details

510(k) Number K231024 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received April 11, 2023
Decision Date August 30, 2023
Days to Decision 141 days
Submission Type Traditional
Review Panel Gastroenterology & Urology (GU)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
11d slower than avg
Panel avg: 130d · This submission: 141d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code PZP Fluid Jet Removal System
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 876.4350
Definition The System Is Used For Removal Of Prostate Tissue With A Fluid Jet.
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most Gastroenterology & Urology devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT02505919 Completed Interventional Industry-sponsored

Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue (WATER)

A Prospective Multicenter Randomized Blinded Study Comparing Aquablation of the Prostate With the AQUABEAM System and TURP for the Treatment of LUTS

184
Patients (actual)
17
Sites
Treatment
Purpose
Double blind
Masking
Condition studied Benign Prostatic Hyperplasia (BPH)
Study design Parallel
Eligibility Male only · 45 Years+
Principal investigator Peter Gilling, M.D.
Sponsor PROCEPT BioRobotics (industry)
Started 2015-10-30 Primary completion 2017-07-14 Completed 2021-12-16
Primary outcome
Proportion of Subjects With Adverse Events (Clavien-Dindo Grading System Grade 2 or Higher or Any Grade 1 Event Resulting in Persistent Disability)
View full study on ClinicalTrials.gov

Regulatory Peers - PZP Fluid Jet Removal System

Devices cleared under the same product code (PZP) and FDA review panel - the closest regulatory comparables to K231024.
HYDROS Robotic System (HY1000)
K251082 · Procept Biorobotics · Oct 2025
AQUABEAM Robotic System (AB2000)
K241952 · Procept Biorobotics · Sep 2024
HYDROS Robotic System
K240200 · Procept Biorobotics · Aug 2024
AquaBeam Robotic System
K212835 · Procept Biorobotics, Corporation · Oct 2021
AquaBeam Robotic System
K202961 · Procept Biorobotics, Corporation · Mar 2021