Cleared Traditional

K232865 - Magseed Pro Magnetic Marker System (FDA 510(k) Clearance)

Class II General & Plastic Surgery device cleared through predicate-based substantial equivalence.

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Jun 2024
Decision
287d
Days
Class 2
Risk

K232865 is an FDA 510(k) clearance for the Magseed Pro Magnetic Marker System. Classified as Marker, Radiographic, Implantable (product code NEU), Class II - Special Controls.

Submitted by Endomagnetics Ltd., (Cambridge, GB). The FDA issued a Cleared decision on June 28, 2024 after a review of 287 days - an extended review cycle.

This device falls under the General & Plastic Surgery FDA review panel, regulated under 21 CFR 878.4300 - the FDA general and plastic surgery device framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the General & Plastic Surgery review framework, consistent with the majority of Class II 510(k) submissions.

View all Endomagnetics Ltd., devices

Submission Details

510(k) Number K232865 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received September 15, 2023
Decision Date June 28, 2024
Days to Decision 287 days
Submission Type Traditional
Review Panel General & Plastic Surgery (SU)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
173d slower than avg
Panel avg: 114d · This submission: 287d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code NEU Marker, Radiographic, Implantable
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 878.4300
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most General & Plastic Surgery devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT05142787 Recruiting Interventional Industry-sponsored

Magseed Pro(R)/ Sentimag(R) Gen3

A Prospective, Multi Center, International, Open Label Study of the Use of Magseed Pro(R) Markers and Sentimag(R) Gen3 to Localize Breast Lesions and Suspicious/biopsy-proven Positive Lymph Nodes in Breast Cancer Patients

224
Patients (est.)
6
Sites
Other
Purpose
Open label
Masking
Condition studied Breast Cancer
Study design Parallel
Eligibility All sexes · 18 Years+
Principal investigator Stefan Paepke, Dr
Sponsor Endomagnetics Ltd. (industry)
Started 2023-03-02 Primary completion 2025-12-31 Completed 2026-06-30
Primary outcome
The primary endpoints are the retrieval rates of the Magseed Pro® marker with the target lesion within the initial excised specimen for A.) axillary lymph nodes B.) breast lesions A.) axillary lymph nodes. B.) breast lesions
Secondary outcome
Tissue response (unexpected and expected)
View full study on ClinicalTrials.gov

Regulatory Peers - NEU Marker, Radiographic, Implantable

All 109
Devices cleared under the same product code (NEU) and FDA review panel - the closest regulatory comparables to K232865.
HydroMARK™ Plus Breast Biopsy Site Marker (Dragonfly Shape)
K253761 · Devicor Medical Products, Inc. · Jan 2026
MOLLI 2 System
K253888 · Stryker Endoscopy · Dec 2025
SCOUT MD Surgical Guidance System
K252892 · Merit Medical Systems, Inc. · Dec 2025
VizMark Preloaded Tissue Marker Device (VM-0001)
K251989 · Breast-Med, Inc. · Dec 2025
MammoSTAR Biopsy Site Identifier
K251748 · Carbon Medical Technologies, Inc. · Jul 2025
UltraCor™ Twirl™ Breast Tissue Marker
K243642 · Bard Peripheral Vascular, Inc. · Mar 2025