Cleared Traditional

K243967 - ONE Nitrile Condom (FDA 510(k) Clearance)

Class II Obstetrics & Gynecology device cleared through predicate-based substantial equivalence.

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Optimized for regulatory review, auditing and printing
Apr 2025
Decision
106d
Days
Class 2
Risk

K243967 is an FDA 510(k) clearance for the ONE Nitrile Condom. Classified as Condom, Synthetic (product code MOL), Class II - Special Controls.

Submitted by Global Protection Corp. (Boston, US). The FDA issued a Cleared decision on April 8, 2025 after a review of 106 days - within the typical 510(k) review window.

This device falls under the Obstetrics & Gynecology FDA review panel, regulated under 21 CFR 884.5300 - the FDA obstetrics and gynecology device framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Standard predicate reliance. This clearance follows a standard predicate-based equivalence path within the Obstetrics & Gynecology review framework, consistent with the majority of Class II 510(k) submissions.

View all Global Protection Corp. devices

Submission Details

510(k) Number K243967 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received December 23, 2024
Decision Date April 08, 2025
Days to Decision 106 days
Submission Type Traditional
Review Panel Obstetrics & Gynecology (OB)
Summary Statement
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
54d faster than avg
Panel avg: 160d · This submission: 106d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code MOL Condom, Synthetic
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 884.5300
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most Obstetrics & Gynecology devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT06079060 Completed Interventional Industry-sponsored

Evaluation of Synthetic Nitrile Male Condom Compared to Standard Latex Male Condom

A Functional Performance and Acceptability Evaluation of Synthetic Nitrile Male Condom Compared to a Standard Latex Male Condom

305
Patients (actual)
3
Sites
Prevention
Purpose
Triple
Masking
Condition studied Sexually Transmitted Diseases
Study design Crossover
Eligibility All sexes · 18 Years+ · Healthy volunteers accepted
Principal investigator Mags Beksinska, PhD
Sponsor Karex Industries Sdn. Bhd. (industry)
Started 2023-10-06 Primary completion 2024-09-30 Completed 2024-10-11
Primary outcome
Clinical breakage
Secondary outcome
Genital discomfort
Study completed - no results published. This trial concluded in 2024 but has not posted results to ClinicalTrials.gov. Completed studies without public results are common in industry-sponsored device trials; the data may be referenced in the 510(k) Summary PDF or remain unpublished. Individual participant data will not be shared.
View full study on ClinicalTrials.gov

Regulatory Peers - MOL Condom, Synthetic

All 21
Devices cleared under the same product code (MOL) and FDA review panel - the closest regulatory comparables to K243967.
Durex Polyisoprene Condom
K241617 · Rb Health (Us), LLC · Feb 2025
TROJAN SIS Synthetic Latex Condom with Silicone Lubricant
K240379 · Church & Dwight Co., Inc. · Oct 2024
ONE Nitrile Condom
K240896 · Global Protection Corp. · Aug 2024
Polyisoprene Extra Large Condom
K232470 · Suretex Limited · May 2024
45 Micron Polyisoprene Condom
K231908 · Suretex Limited · Oct 2023
Okamoto 002 Lubricated Polyurethane Male Condom
K203541 · Okamoto USA, Inc. · Feb 2022