Cleared Traditional

K250258 - HeartBeam AIMIGo with 12-L ECG Synthesis Software System (FDA 510(k) Clearance)

Class II Cardiovascular device cleared through predicate-based substantial equivalence.

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Dec 2025
Decision
314d
Days
Class 2
Risk

K250258 is an FDA 510(k) clearance for the HeartBeam AIMIGo with 12-L ECG Synthesis Software System. Classified as Transmitters And Receivers, Electrocardiograph, Telephone (product code DXH), Class II - Special Controls.

Submitted by Heartbeam, Inc. (Santa Clara, US). The FDA issued a Cleared decision on December 8, 2025 after a review of 314 days - an unusually long review period, suggesting complex equivalence evaluation.

This device falls under the Cardiovascular FDA review panel, regulated under 21 CFR 870.2920 - the FDA cardiovascular device oversight framework. The Traditional 510(k) pathway establishes clearance through substantial equivalence to a legally marketed predicate device, without requiring clinical trial data.

Device pattern: Standard predicate-based submission. Elevated predicate reliance profile. This clearance follows a standard predicate-based equivalence path within the Cardiovascular review framework, consistent with the majority of Class II 510(k) submissions.

View all Heartbeam, Inc. devices

Submission Details

510(k) Number K250258 FDA.gov
FDA Decision Cleared Substantially Equivalent - Traditional 510(k) (SESE)
Date Received January 28, 2025
Decision Date December 08, 2025
Days to Decision 314 days
Submission Type Traditional
Review Panel Cardiovascular (CV)
Summary Summary PDF
Third-party Review No - reviewed directly by FDA
Combination Product No
PCCP Authorized No
Regulatory Context
Review time vs. panel average
189d slower than avg
Panel avg: 125d · This submission: 314d
Pathway characteristics
Predicate-based equivalence.

Device Classification

Product Code DXH Transmitters And Receivers, Electrocardiograph, Telephone
Device Class Class 2 - Special Controls
CFR Regulation 21 CFR 870.2920
What this classification means

Class II devices require demonstration of substantial equivalence to a legally marketed predicate device. Clinical trial data may be submitted as supporting evidence to strengthen the substantial equivalence argument. Most Cardiovascular devices follow this clearance model.

Clinical Evidence

ClinicalTrials.gov
NCT06123130 Completed Interventional Industry-sponsored

AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection

Clinical Validation of the AIMIGo 12 Lead ECG Synthesis Software for Arrhythmia Detection: A Prospective Multicenter Pivotal Study

198
Patients (actual)
5
Sites
Diagnostic
Purpose
Open label
Masking
Condition studied Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Tachycardia
Study design Single group
Eligibility All sexes · 18 Years+
Principal investigator Peter J. Fitzgerald, MD, PhD
Sponsor HeartBeam, Inc. (industry)
Started 2024-03-13 Primary completion 2024-06-20
Primary outcome
Clinical equivalence of ECG intervals compared between AIMIGo Synthesized 12L and reference standard 12L
Secondary outcome
Clinical diagnostic accuracy of AIMIGo Synthesized 12L compared with the reference standard 12L ECG for the classification of arrhythmia.
Study completed - no results published. This trial concluded in 2024 but has not posted results to ClinicalTrials.gov. Completed studies without public results are common in industry-sponsored device trials; the data may be referenced in the 510(k) Summary PDF or remain unpublished. Individual participant data will not be shared.
View full study on ClinicalTrials.gov

Regulatory Peers - DXH Transmitters And Receivers, Electrocardiograph, Telephone

All 296
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