KDI · Class II · 21 CFR 876.5860

FDA Product Code KDI: Dialyzer, High Permeability With Or Without Sealed Dialysate System

High-flux dialysis has transformed the standard of care for patients with end-stage renal disease. FDA product code KDI covers high permeability dialyzers.

These devices use semipermeable membranes with large pore sizes to remove both small and larger uremic toxins from the blood during hemodialysis. High permeability dialyzers have largely replaced low-flux membranes due to their superior clearance of middle molecules linked to long-term complications.

KDI devices are Class II medical devices, regulated under 21 CFR 876.5860 and reviewed by the FDA Gastroenterology & Urology panel.

Leading manufacturers include Fresenius Medical Care Renal Therapies Group, LLC, Baxter Healthcare Corporation and Outset Medical, Inc..

343
Total
343
Cleared
176d
Avg days
1978
Since
Stable submission activity - 15 submissions in the last 2 years
Consistent review times: 178d avg (recent)

FDA 510(k) Cleared Dialyzer, High Permeability With Or Without Sealed Dialysate System Devices (Product Code KDI)

343 devices
1–24 of 343
Cleared Mar 19, 2026
ELISIO™-H
K260533
Nipro Medical Corporation
Gastroenterology & Urology · 30d
Cleared Feb 10, 2026
multiFlux 130 (F00013123)
K252459
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 189d
Cleared Jan 26, 2026
Tablo Hemodialysis System (PN-0008000, PN-0006000U)
K253412
Outset Medical, Inc.
Gastroenterology & Urology · 118d
Cleared Dec 18, 2025
FX CorAL 40
K253518
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 36d
Cleared Sep 19, 2025
Purema H Hemoconcentrator - Pediatric
K243920
Medica USA, Inc.
Gastroenterology & Urology · 273d
Cleared Aug 01, 2025
AK 98 Dialysis Machine (955607)
K250508
Vantive US Healthcare, LLC
Gastroenterology & Urology · 161d
Cleared Jun 13, 2025
2008T HD SYS. CDX BLUESTAR (191124)
K243237
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 246d
Cleared May 30, 2025
5008X Hemodialysis System
K243505
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 199d
Cleared May 15, 2025
DBB-06 PRO Hemodialysis Delivery System (DBB-06 PRO)
K242155
NIKKISO CO., LTD.
Gastroenterology & Urology · 296d
Cleared Apr 25, 2025
DHF 0.2 Hemoconcentrator (DHF 02)
K243264
Sorin Group Italia S.R.L.
Gastroenterology & Urology · 192d
Cleared Mar 21, 2025
FX CorAL 40 (F00009214)
K242053
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 252d
Cleared Feb 28, 2025
FX CorAL 60 (F00012969)
K243874
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 73d
Cleared Aug 02, 2024
Moda-flx Hemodialysis System and Cartridge
K233798
Diality, Inc.
Gastroenterology & Urology · 247d
Cleared Jul 12, 2024
HemoCare Hemodialysis System
K233557
Deka Research and Development
Gastroenterology & Urology · 249d
Cleared May 31, 2024
multiFlux 1000 (F00012408)
K240394
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 113d
Cleared May 03, 2024
Tablo® Hemodialysis System
K232776
Outset Medical, Inc.
Gastroenterology & Urology · 235d
Cleared Mar 14, 2024
NxStage System One with Cartridge Express (CAR-170-E and CAR-172-E)
K232803
Nxstage Medical, Inc.
Gastroenterology & Urology · 184d
Cleared Feb 07, 2024
Purema® H Hemoconcentrator (EtO Sterilized)
K232171
Tecnoideal America
Gastroenterology & Urology · 201d
Cleared Feb 02, 2024
5008X Hemodialysis System
K231534
Fresenius Medical Care
Gastroenterology & Urology · 248d
Cleared Dec 06, 2023
2008T BlueStar Hemodialysis Machine
K231125
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 230d
Cleared Sep 14, 2023
CleanCart A, CleanCart C, AK 98 Hemodialysis Machine
K232467
Baxter Healthcare Corporation
Gastroenterology & Urology · 30d
Cleared Aug 11, 2023
VersiHD with GuideMe software
K230632
Nxstage Medical, Inc.
Gastroenterology & Urology · 157d
Cleared May 11, 2023
FX CorAL 60, FX CorAL 80, FX CorAL 100, FX CorAL 120, FX CorAL 600, FX CorAL 800, FX CorAL 1000
K220721
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 423d
Cleared Dec 16, 2022
multiFiltratePRO System
K220281
Fresenius Medical Care Renal Therapies Group, LLC
Gastroenterology & Urology · 318d

About Product Code KDI - Regulatory Context

510(k) Submission Activity

343 total 510(k) submissions under product code KDI since 1978, with 343 receiving FDA clearance (average review time: 176 days).

Submission volume has remained relatively stable over the observed period, with 15 submissions in the last 24 months.

FDA Review Time

FDA review times for KDI submissions have been consistent, averaging 178 days recently vs 176 days historically.

KDI devices are reviewed by the Gastroenterology & Urology panel. Browse all Gastroenterology & Urology devices →