KNW · Class II · 21 CFR 876.1075

FDA Product Code KNW: Instrument, Biopsy

Tissue biopsy is the definitive diagnostic procedure in oncology and pathology. FDA product code KNW covers biopsy instruments used to obtain tissue samples for histopathological analysis.

These devices use needle-based, vacuum-assisted, or mechanical cutting mechanisms to remove representative tissue cores from suspect lesions. They are used across specialties including breast surgery, urology, gastroenterology, and interventional radiology.

KNW devices are Class II medical devices, regulated under 21 CFR 876.1075 and reviewed by the FDA General & Plastic Surgery panel.

Leading manufacturers include Zhejiang Curaway Medical Technology Co., Ltd., Senorx, Inc. and Promisemed Hangzhou Meditech Co., Ltd..

360
Total
360
Cleared
99d
Avg days
1976
Since
Growing category - 18 submissions in the last 2 years vs 13 in the prior period
Review times increasing: avg 160d recently vs 95d historically

FDA 510(k) Cleared Instrument, Biopsy Devices (Product Code KNW)

360 devices
1–24 of 360
Cleared Mar 04, 2026
Mammotome Prima™ MR Dual Vacuum-Assisted Breast Biopsy System Control Module
K260365
Devicor Medical Products, Inc.
General & Plastic Surgery · 28d
Cleared Feb 23, 2026
ZeniCore™ Automatic Biopsy Instrument (863212100 / ZeniCore Automatic Biopsy Device 12ga x 10cm with Coaxial Introducer Kit)
K252795
Argon Medical Devices, Inc.
General & Plastic Surgery · 174d
Cleared Dec 12, 2025
EnCor EnCompass™ Breast Biopsy and Tissue Removal System
K252681
Bard Peripheral Vascular, Inc.
General & Plastic Surgery · 109d
Cleared Sep 24, 2025
Resitu Slider 09 (RESL09)
K252183
Resitu Medical AB
General & Plastic Surgery · 75d
Cleared Jul 29, 2025
Forcyte Autograft Harvest Kit
K243407
Forcyte Medical, LLC
Orthopedic · 270d
Cleared Jul 22, 2025
Disposable Biopsy Needle
K244018
Zhejiang Curaway Medical Technology Co., Ltd.
General & Plastic Surgery · 207d
Cleared Jul 11, 2025
Disposable Biopsy Needle
K243296
Carbon (Shenzhen) Medical Device Co., Ltd.
General & Plastic Surgery · 266d
Cleared Jul 10, 2025
Marquee™ Disposable Core Biopsy Instrument and Instrument Kit
K250032
Bard Peripheral Vascular, Inc.
General & Plastic Surgery · 184d
Cleared Apr 29, 2025
ExpressCore Biopsy Device
K243886
Inrad, Inc.
General & Plastic Surgery · 132d
Cleared Apr 24, 2025
ALARA BMA Neuro Access Kit (ALARA BMAN and ALARA BMAC Kit)
K243945
SurGenTec, LLC
General & Plastic Surgery · 125d
Cleared Feb 27, 2025
Forsvall biopsy needle system for prostate biopsy (Forsvall biopsy gun and Forsvall biopsy needle)
K242128
Xaga Surgical
Gastroenterology & Urology · 223d
Cleared Jan 24, 2025
Automatic Core Biopsy Instrument/ Semi-Automatic Core Biopsy Instrument/ Disposable Coaxial Biopsy Needle
K241793
Zhejiang Curaway Medical Technology Co., Ltd.
General & Plastic Surgery · 217d
Cleared Jan 24, 2025
Bone Marrow Biopsy Needle
K242322
Zhejiang Curaway Medical Technology Co., Ltd.
General & Plastic Surgery · 171d
Cleared Jan 10, 2025
Triopsy Actuator (TMSDGB)
K242228
Triopsy Medical, Inc.
Gastroenterology & Urology · 164d
Cleared Oct 29, 2024
Mammotome AutoCore™ Single Insertion Core Biopsy System
K243095
Devicor Medical Products, Inc.
General & Plastic Surgery · 29d
Cleared Oct 09, 2024
TRAP EASY
K242029
H.S Hospital Service S.P.A
General & Plastic Surgery · 90d
Cleared Aug 09, 2024
ALARA BMA Neuro Access Kit (ALARA BMAN and ALARA BMAC Kit)
K240664
SurGenTec, LLC
General & Plastic Surgery · 154d
Cleared Jun 18, 2024
Automatic Biopsy Needle BAM, Semi-Automatic Needle BIM
K233294
Itp Innovative Tomography Products GmbH
General & Plastic Surgery · 263d
Cleared Jan 17, 2024
M·Biopsy /SureCore Automatic Disposable Biopsy Needle, M·Biopsy /SureCore Semi-automatic Disposable Biopsy Needle, M·Biopsy /SureAim Coaxial Biopsy Needle
K233031
Canyon Medical, Inc.
General & Plastic Surgery · 114d
Cleared Oct 27, 2023
EnCor Enspire™Breast Biopsy System (E4115, E4230)
K233220
Senorx, Inc.
General & Plastic Surgery · 29d
Cleared Apr 22, 2022
Promisemed Fine Biopsy Needle
K213683
Promisemed Hangzhou Meditech Co., Ltd.
General & Plastic Surgery · 151d
Cleared Nov 19, 2021
Arthrex Vortex Threaded Bone Marrow Recovery Needle
K213213
Arthrex, Inc.
General & Plastic Surgery · 51d
Cleared Aug 12, 2021
Promisemed Automatic Biopsy Needles, Promisemed Co-Axial Biopsy Devices, Promisemed Semi-automatic Biopsy Needles
K210946
Promisemed Hangzhou Meditech Co., Ltd.
General & Plastic Surgery · 135d
Cleared Mar 31, 2021
EnCor Breast Biopsy Probe with Rinse Tube
K210654
Senorx, Inc.
General & Plastic Surgery · 27d

About Product Code KNW - Regulatory Context

510(k) Submission Activity

360 total 510(k) submissions under product code KNW since 1976, with 360 receiving FDA clearance (average review time: 99 days).

Submission volume has increased in recent years - 18 submissions in the last 24 months compared to 13 in the prior period - suggesting growing market activity in this device classification.

FDA Review Time

Recent submissions under KNW have taken an average of 160 days to reach a decision - up from 95 days historically. Manufacturers should account for longer review timelines in current project planning.

KNW devices are reviewed by the General & Plastic Surgery panel. Browse all General & Plastic Surgery devices →