KWS · Class II · 21 CFR 888.3660

FDA Product Code KWS: Prosthesis, Shoulder, Semi-constrained, Metal/polymer Cemented

Under FDA product code KWS, semi-constrained shoulder prostheses with metal and polymer bearing surfaces are cleared for total shoulder arthroplasty.

These anatomical shoulder replacement systems reproduce the natural ball-and-socket geometry of the glenohumeral joint, with a metal humeral head articulating against a polymer glenoid component. They are indicated for patients with intact or repairable rotator cuff function.

KWS devices are Class II medical devices, regulated under 21 CFR 888.3660 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include Smith & Nephew, Inc., Arthrex, Inc. and Encore Medical, L.P..

190
Total
190
Cleared
117d
Avg days
1980
Since
Stable submission activity - 6 submissions in the last 2 years
Review times increasing: avg 137d recently vs 116d historically

FDA 510(k) Cleared Prosthesis, Shoulder, Semi-constrained, Metal/polymer Cemented Devices (Product Code KWS)

190 devices
1–24 of 190
Cleared Apr 06, 2026
AETOS Shoulder System - CONCELOC Glenoids
K254084
Smith & Nephew, Inc.
Orthopedic · 109d
Cleared Nov 06, 2025
Catalyst F1x Shoulder System
K252418
Catalyst Orthoscience, Inc.
Orthopedic · 97d
Cleared Oct 29, 2025
AETOS Shoulder System Meta Humeral Prosthesis Size 0
K252416
Smith & Nephew, Inc.
Orthopedic · 89d
Cleared Jan 30, 2025
MyShoulder Planner (5.3SSWPL)
K241292
Medacta International S.A.
Orthopedic · 267d
Cleared Dec 06, 2024
Tornier Humeral Reconstruction System (Tornier HRS)
K241878
Stryker Corporation (Tornier, Inc.)
Orthopedic · 161d
Cleared Sep 10, 2024
Tornier Humeral Reconstruction System (Tornier HRS)
K241609
Stryker Corporation (Tornier, Inc.)
Orthopedic · 97d
Cleared Sep 26, 2023
Arthrex Univers Apex OptiFit Humeral Stem
K230513
Arthrex, Inc.
Orthopedic · 214d
Cleared Jun 23, 2023
AltiVate® Anatomic Shoulder AG e+™ with Markers
K222592
Encore Medical, L.P.
Orthopedic · 301d
Cleared Jun 07, 2023
AETOS Shoulder System
K230572
Smith & Nephew, Inc.
Orthopedic · 98d
Cleared Jan 03, 2023
AETOS Shoulder System
K220847
Smith & Nephew, Inc.
Orthopedic · 286d
Cleared Jul 07, 2022
AltiVate® Anatomic Shoulder AG e+™ with Markers
K213387
Encore Medical, L.P.
Orthopedic · 266d
Cleared Mar 11, 2022
TITAN Total Shoulder System (TSS), TITAN Reverse Shoulder System (RSS), TITAN Humeral Resurfacing Arthroplasty System (HRA), Modular Radial Head System (MRH), Katalyst Bipolar Radial Head System (Katalyst)
K213827
Smith & Nephew, Inc.
Orthopedic · 93d
Cleared Mar 04, 2022
Exactech® Equinoxe® Laser Cage Glenoid
K212356
Exactech, Inc.
Orthopedic · 218d
Cleared Dec 10, 2021
Comprehensive Humeral Fracture Positioning Sleeves
K212435
Biomet, Inc.
Orthopedic · 128d
Cleared Sep 03, 2021
ReUnion Reversible Fracture System (RFX), ReUnion Reverse Shoulder Arthroplasty System (RSA), ReUnion Total Shoulder Arthroplasty System (TSA)
K210861
Stryker GmbH
Orthopedic · 164d
Cleared Jun 07, 2021
Augmented VaultLock Glenoid
K210050
Arthrex, Inc.
Orthopedic · 150d
Cleared Apr 15, 2021
BLUEPRINT™ Patient Specific Instrumentation
K203315
Tornier S.A.S.
Orthopedic · 156d

About Product Code KWS - Regulatory Context

510(k) Submission Activity

190 total 510(k) submissions under product code KWS since 1980, with 190 receiving FDA clearance (average review time: 117 days).

Submission volume has remained relatively stable over the observed period, with 6 submissions in the last 24 months.

FDA Review Time

Recent submissions under KWS have taken an average of 137 days to reach a decision - up from 116 days historically. Manufacturers should account for longer review timelines in current project planning.

KWS devices are reviewed by the Orthopedic panel. Browse all Orthopedic devices →