LHI · Class II · 21 CFR 880.5440

FDA Product Code LHI: Set, I.v. Fluid Transfer

Under FDA product code LHI, IV fluid transfer sets are cleared for the transfer of sterile fluids between containers.

These sterile, closed-system tubing sets enable aseptic transfer of intravenous solutions from bulk containers to IV bags or bottles without exposing the fluid to the environment. They are used in pharmacy compounding and clinical preparation of IV admixtures.

LHI devices are Class II medical devices, regulated under 21 CFR 880.5440 and reviewed by the FDA General Hospital panel.

Leading manufacturers include Hangzhou Qiantang Longyue Biotechnology Co., Ltd., Sfm Medical Devices GmbH and Yukon Medical, LLC.

205
Total
205
Cleared
123d
Avg days
1981
Since
Declining activity - 10 submissions in the last 2 years vs 15 in the prior period
Review times increasing: avg 183d recently vs 120d historically

FDA 510(k) Cleared Set, I.v. Fluid Transfer Devices (Product Code LHI)

205 devices
1–24 of 205
Cleared Oct 24, 2025
Medline Bag Decanter
K250345
Medline Industries, LP
General Hospital · 260d
Cleared Oct 14, 2025
FlowArt® Vial Access Device Vented
K251715
Asset Medikal
General Hospital · 132d
Cleared Sep 16, 2025
Medline Microtek C-Flo Bag Decanter, Sterile (2000S)
K251676
Microtek Medical, LLC
General Hospital · 109d
Cleared Jul 18, 2025
HyHub™ and HyHub™ Duo Vial Access Devices
K243404
Takeda Pharmaceuticals
General Hospital · 259d
Cleared Mar 21, 2025
Arisure® Closed Male Luer with Spike Adapter (YM060)
K240761
Yukon Medical, LLC
General Hospital · 366d
Cleared Jan 22, 2025
Rio™ Drug Reconstitution Transfer Device
K243985
Icu Medical, Inc.
General Hospital · 30d
Cleared Dec 06, 2024
SmartSiteTM Vented Vial Access Device
K243486
Yukon Medical, LLC
General Hospital · 28d
Cleared Sep 06, 2024
nextaro® va, 15mm, 5µm
K241976
Sfm Medical Devices GmbH
General Hospital · 63d
Cleared Jul 26, 2024
Vent Vial Adapter
K233287
Hangzhou Qiantang Longyue Biotechnology Co., Ltd.
General Hospital · 301d
Cleared Jun 26, 2024
FlowArt Valve for Vial Access
K232987
Asset Medikal Tasarim Sanayi VE Ticaret A.S.
General Hospital · 278d
Cleared May 03, 2024
Vial2Bag Advanced® 20mm Admixture Device
K240940
West Pharmaceutical Services, Inc.
General Hospital · 28d
Cleared May 01, 2024
Vial Adapter with Filter
K233284
Hangzhou Qiantang Longyue Biotechnology Co., Ltd.
General Hospital · 215d
Cleared Apr 16, 2024
nextaro® v, 20/20
K240748
Sfm Medical Devices GmbH
General Hospital · 28d
Cleared Mar 06, 2024
BD SmartSite™ 13mm Vial Access Device
K233021
Care Fusion
General Hospital · 166d
Cleared Jan 19, 2024
Mix2Vial® Transfer Device
K231071
West Pharma Services Il, Ltd.
General Hospital · 280d
Cleared Oct 28, 2022
Vented Vial Transfer Pin
K221406
Jiangsu Caina Medical Co.,Ltd
General Hospital · 165d

About Product Code LHI - Regulatory Context

510(k) Submission Activity

205 total 510(k) submissions under product code LHI since 1981, with 205 receiving FDA clearance (average review time: 123 days).

Submission volume has declined in recent years - 10 submissions in the last 24 months compared to 15 in the prior period.

FDA Review Time

Recent submissions under LHI have taken an average of 183 days to reach a decision - up from 120 days historically. Manufacturers should account for longer review timelines in current project planning.

LHI devices are reviewed by the General Hospital panel. Browse all General Hospital devices →