MAI · Class II · 21 CFR 888.3030

FDA Product Code MAI: Fastener, Fixation, Biodegradable, Soft Tissue

Biodegradable fixation eliminates the need for hardware removal surgery in soft tissue repair. FDA product code MAI covers biodegradable soft tissue fixation fasteners.

These implants anchor tendons and ligaments to bone during reconstructive procedures and gradually resorb as the tissue heals, leaving no permanent implant in the body. They are used in ACL reconstruction, rotator cuff repair, and other sports medicine procedures.

MAI devices are Class II medical devices, regulated under 21 CFR 888.3030 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include Arthrex, Inc., Osteonic Co., Ltd. and OSSIO , Ltd..

219
Total
219
Cleared
108d
Avg days
1994
Since
Stable submission activity - 15 submissions in the last 2 years
Review times improving: avg 83d recently vs 110d historically

FDA 510(k) Cleared Fastener, Fixation, Biodegradable, Soft Tissue Devices (Product Code MAI)

219 devices
1–24 of 219
Cleared Mar 27, 2026
SF Push-in Anchor
K260294
Surgical Fusion Technologies GmbH
Orthopedic · 57d
Cleared Feb 24, 2026
OSSIOfiber® Suture Anchor
K254055
OSSIO , Ltd.
Orthopedic · 69d
Cleared Feb 17, 2026
Biosteon® Screw
K251680
Biocomposites, Ltd.
Orthopedic · 263d
Cleared Oct 15, 2025
BioBrace® Extra-Articular Ligament Augmentation Kit
K252946
Conmed Corporation
Orthopedic · 30d
Cleared Aug 19, 2025
OSSIOfiber® Interference Screw
K252022
OSSIO , Ltd.
Orthopedic · 50d
Cleared May 27, 2025
OSSIOfiber® Suture Anchor
K251309
OSSIO , Ltd.
Orthopedic · 29d
Cleared May 23, 2025
Knotilus+ Biocomposite Knotless Anchor
K250544
Stryker Endoscopy
Orthopedic · 87d
Cleared May 21, 2025
Stryker AlphaVent™ Knotless SP Biocomposite Anchor
K250528
Stryker Endoscopy
Orthopedic · 86d
Cleared Apr 03, 2025
OSSIOfiber® Suture Anchor 2.5-3.5 mm
K243760
OSSIO , Ltd.
Orthopedic · 118d
Cleared Mar 14, 2025
Arthrex 4.75 mm Double Loaded Knotless Corkscrew Suture Anchor
K250526
Arthrex, Inc.
Orthopedic · 18d
Cleared Feb 05, 2025
GRYPHON™ X Anchor
K243790
Depuy Mitek
Orthopedic · 57d
Cleared Dec 03, 2024
Fix2Lock (Biocomposite medial, Biocomposite lateral, Biocombi Self Punching)
K243467
Osteonic Co., Ltd.
Orthopedic · 25d
Cleared Sep 11, 2024
HEALIX ADVANCE Knotless anchors
K241010
Depuy Mitek
Orthopedic · 152d
Cleared Jul 29, 2024
BIOCHARGE
K241912
Nanofiber Solutions, LLC
Orthopedic · 28d
Cleared Jun 04, 2024
Arthrex AlloSync PushLock Suture Anchor
K233971
Arthrex, Inc.
Orthopedic · 172d
Cleared Apr 01, 2024
SF Push- in Anchor
K240288
Surgical Fusion Technologies GmbH
Orthopedic · 60d
Cleared Mar 15, 2024
MILAGRO Interference Screw
K240441
Depuy Mitek
Orthopedic · 30d
Cleared Mar 05, 2024
Argo Knotless GENESYS Anchor
K240090
Conmed Corporation
Orthopedic · 53d
Cleared May 31, 2023
Fix2Lock(Biocomposite medial, lateral, Biocombi Self Punching)
K231326
Osteonic Co., Ltd.
Orthopedic · 23d
Cleared Mar 17, 2023
Arthrex 3.9 mm SwiveLock Anchor
K230435
Arthrex, Inc.
Orthopedic · 28d
Cleared Oct 05, 2022
Arthrex ACL TightRope®, PCL TightRope®, and TightRope® II
K221128
Arthrex, Inc.
Orthopedic · 170d
Cleared Aug 26, 2022
Arthrex Self Punching SwiveLock Suture Anchors
K222263
Arthrex, Inc.
Orthopedic · 29d
Cleared May 13, 2022
Arthrex Self-Punching PushLock Suture Anchor
K221099
Arthrex, Inc.
Orthopedic · 29d
Cleared Aug 27, 2021
Sterile Bioabsorbable bone screw (Bioabsorbable ACL screw)
K210122
Osteonic Co., Ltd.
Orthopedic · 220d

About Product Code MAI - Regulatory Context

510(k) Submission Activity

219 total 510(k) submissions under product code MAI since 1994, with 219 receiving FDA clearance (average review time: 108 days).

Submission volume has remained relatively stable over the observed period, with 15 submissions in the last 24 months.

FDA Review Time

Recent submissions under MAI have taken an average of 83 days to reach a decision - down from 110 days historically, suggesting improved FDA processing for this classification.

MAI devices are reviewed by the Orthopedic panel. Browse all Orthopedic devices →