MEH · Class II · 21 CFR 888.3353

FDA Product Code MEH: Prosthesis, Hip, Semi-constrained, Uncemented, Metal / Polymer, Non-porous, Calcium Phosphate

FDA product code MEH covers uncemented semi-constrained hip prostheses with metal bearing surfaces.

These implants rely on biological fixation — bone ingrowth or ongrowth into a porous-coated surface — rather than bone cement for long-term stability. Uncemented fixation is the preferred approach in younger, more active patients due to its potential for longer implant longevity.

MEH devices are Class II medical devices, regulated under 21 CFR 888.3353 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include Signature Orthopaedics Pty, Ltd., Depuy Ireland UC and Conformis, Inc..

159
Total
159
Cleared
157d
Avg days
1990
Since
Growing category - 9 submissions in the last 2 years vs 6 in the prior period
Review times improving: avg 116d recently vs 159d historically

FDA 510(k) Cleared Prosthesis, Hip, Semi-constrained, Uncemented, Metal / Polymer, Non-porous, Calcium Phosphate Devices (Product Code MEH)

159 devices
1–24 of 159
Cleared Nov 05, 2025
Allure Hip Stem and Intramedullary Plugs
K250375
Waldemar Link GmbH & Co. KG
Orthopedic · 268d
Cleared Jun 13, 2025
Mfinity Femoral System
K251166
Medacta International S.A.
Orthopedic · 59d
Cleared May 22, 2025
Trivicta® Hip Stem
K251052
Ortho Development Corp.
Orthopedic · 49d
Cleared May 01, 2025
Resolve Modular Revision Hip Stem
K242315
United Orthopedic Corporation
Orthopedic · 269d
Cleared Mar 10, 2025
Alteon® HA Femoral Stems
K243839
Exactech, Inc.
Orthopedic · 87d
Cleared Nov 25, 2024
World Liner
K243162
Signature Orthopaedics Pty, Ltd.
Orthopedic · 56d
Cleared Oct 03, 2024
Icona Hip Stem
K241472
Corin U.S.A. Limited
Orthopedic · 132d
Cleared Sep 13, 2024
TheRay Collared and Collarless Femoral Stem
K241875
Nextstep Arthropedix
Orthopedic · 77d
Cleared Aug 01, 2024
Logical Liner
K241690
Signature Orthopaedics Pty, Ltd.
Orthopedic · 50d
Cleared Mar 08, 2024
Trivicta™ Hip Stem
K233758
Ortho Development Corp.
Orthopedic · 105d
Cleared Jan 19, 2024
DePuy SUMMIT Porocoat Hip Prosthesis – MR Conditional, DePuy SUMMIT DuoFix Hip Prosthesis – MR Conditional, DePuy SUMMIT Cemented Hip Prosthesis – MR Conditional, DePuy SUMMIT FX Cemented Hip Prosthesis – MR Conditional, DePuy SUMMIT Basic Press-Fit Hip Prosthesis – MR Conditional
K231873
Depuy Ireland UC
Orthopedic · 207d
Cleared May 23, 2023
ACTERA™ hip system
K231178
Conformis, Inc.
Orthopedic · 27d
Cleared Jan 13, 2023
SignaSure Dual Mobility System
K220495
Signature Orthopaedics Pty, Ltd.
Orthopedic · 325d
Cleared Aug 11, 2022
Insignia Hip Stem, Restoration Modular 115mm Conical Distal Stem
K220731
Stryker
Orthopedic · 150d
Cleared Aug 04, 2022
Actera™ hip system
K221104
Conformis, Inc.
Orthopedic · 112d
Cleared Jan 07, 2022
SignaSure Dual Mobility System
K211742
Signature Orthopaedics Pty, Ltd.
Orthopedic · 214d
Cleared Sep 24, 2021
Encore Hip Stem
K211505
Signature Orthopaedics Pty, Ltd.
Orthopedic · 133d
Cleared Aug 16, 2021
Insignia Hip Stem
K211703
Stryker Orthopaedics
Orthopedic · 74d
Cleared May 20, 2021
Actis DuoFix Hip Prosthesis- Collarless
K210581
Depuy Ireland UC
Orthopedic · 83d

About Product Code MEH - Regulatory Context

510(k) Submission Activity

159 total 510(k) submissions under product code MEH since 1990, with 159 receiving FDA clearance (average review time: 157 days).

Submission volume has increased in recent years - 9 submissions in the last 24 months compared to 6 in the prior period - suggesting growing market activity in this device classification.

FDA Review Time

Recent submissions under MEH have taken an average of 116 days to reach a decision - down from 159 days historically, suggesting improved FDA processing for this classification.

MEH devices are reviewed by the Orthopedic panel. Browse all Orthopedic devices →