FDA Product Code NPM: Bone Grafting Material, Animal Source

Animal-derived bone grafting materials provide a natural scaffold for bone regeneration. FDA product code NPM covers animal-source bone grafting materials used in dental surgery.

These xenograft materials — typically derived from bovine or porcine bone — are processed to remove organic components while preserving the mineral scaffold, providing a biocompatible matrix that supports new bone formation in extraction sockets, sinus lifts, and periodontal defects.

NPM devices are Class II medical devices, regulated under 21 CFR 872.3930 and reviewed by the FDA Dental panel.

Leading manufacturers include Collagen Matrix, Inc., Geistlich Pharma AG and Purgo Biologics, Inc..