OVE · Class II · 21 CFR 888.3080

FDA Product Code OVE: Intervertebral Fusion Device With Integrated Fixation, Cervical

FDA product code OVE covers cervical intervertebral fusion devices with integrated fixation.

These single-piece implants combine an interbody spacer with integrated anterior fixation screws or blades, providing both disc space support and vertebral stabilization without a separate plate. They are used in one- or two-level anterior cervical discectomy and fusion procedures.

OVE devices are Class II medical devices, regulated under 21 CFR 888.3080 and reviewed by the FDA Orthopedic panel.

Leading manufacturers include SeaSpine Orthopedics Corporation, GS Medical Co., Ltd. and Elevation Spine.

160
Total
160
Cleared
135d
Avg days
2007
Since
Declining activity - 17 submissions in the last 2 years vs 27 in the prior period
Review times improving: avg 108d recently vs 138d historically

FDA 510(k) Cleared Intervertebral Fusion Device With Integrated Fixation, Cervical Devices (Product Code OVE)

160 devices
1–24 of 160
Cleared Apr 27, 2026
SABER-C System
K260660
Elevation Spine
Orthopedic · 56d
Cleared Apr 20, 2026
SAGI Cervical Cage System
K253213
ZheJiang Decans Medical Devices Co., Ltd.
Orthopedic · 203d
Cleared Apr 15, 2026
Uni-C Cervical Cage System
K252774
ZheJiang Decans Medical Devices Co., Ltd.
Orthopedic · 225d
Cleared Feb 04, 2026
E3D™-C Interbody System
K260038
Evolution Spine
Orthopedic · 29d
Cleared Dec 22, 2025
HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer)
K253876
Globus Medical, Inc.
Orthopedic · 18d
Cleared Dec 11, 2025
Cervical Spine Truss System - Stand Alone (CSTS-SA)
K253200
4Web Medical, Inc.
Orthopedic · 76d
Cleared Sep 25, 2025
Endeavor™ Stand-Alone Cervical IBF System
K250076
Innovasis
Orthopedic · 258d
Cleared Aug 08, 2025
SABER-C System
K250540
Elevation Spine
Orthopedic · 165d
Cleared Jul 30, 2025
Stabilis SA Cervical Stand-Alone System (Various PNs)
K251735
Acuity Surgical Devices, LLC
Orthopedic · 54d
Cleared Jun 27, 2025
FIX-C PEEK ACIF SA System
K251431
Jeil Medical Corporation
Orthopedic · 50d
Cleared Apr 25, 2025
Cervical Spine Truss System (CSTS)
K251117
4Web Medical
Orthopedic · 14d
Cleared Apr 10, 2025
Tesera-k SC System
K242928
Kyocera Medical Technologies, Inc.
Orthopedic · 198d
Cleared Feb 11, 2025
CYLOX® ST
K243188
Signus Medizintechnik GmbH
Orthopedic · 134d
Cleared Feb 07, 2025
Genesys Spine AIS-C II Cervical Interbody Fusion System
K242483
Genesys Spine
Orthopedic · 170d
Cleared Nov 20, 2024
ProAM ACDF System
K242517
Pro Surgical, Inc.
Orthopedic · 89d
Cleared Aug 12, 2024
E3D™-C Interbody System
K241846
Evolution Spine
Orthopedic · 47d
Cleared Jul 17, 2024
Stable-C Interbody System
K241467
Nexus Spine, LLC
Orthopedic · 55d
Cleared May 10, 2024
SCARLET® AC-Ti
K240699
Spineart SA
Orthopedic · 57d
Cleared Apr 19, 2024
UniSpace® Stand-Alone C Cage
K234119
Innosys Co., Ltd.
Orthopedic · 113d
Cleared Mar 22, 2024
Idys® C ZP 3DTi
K240715
Clariance
Orthopedic · 7d
Cleared Dec 13, 2023
Genesys Spine 3DP AIS-C II Cervical Interbody System
K233594
Genesys Spine
Orthopedic · 35d
Cleared Nov 28, 2023
Shoreline ACS Interbody System
K233414
SeaSpine Orthopedics Corporation
Orthopedic · 49d
Cleared Oct 27, 2023
RIGEL™ 3DR Standalone Anterior Cervical Interbody Fusion System
K232348
MiRus, LLC
Orthopedic · 81d
Cleared Oct 19, 2023
Pro-Link® & Pro-Link® Ti Barbs Cervical Spacer System
K231704
Life Spine, Inc.
Orthopedic · 129d

About Product Code OVE - Regulatory Context

510(k) Submission Activity

160 total 510(k) submissions under product code OVE since 2007, with 160 receiving FDA clearance (average review time: 135 days).

Submission volume has declined in recent years - 17 submissions in the last 24 months compared to 27 in the prior period.

FDA Review Time

Recent submissions under OVE have taken an average of 108 days to reach a decision - down from 138 days historically, suggesting improved FDA processing for this classification.

OVE devices are reviewed by the Orthopedic panel. Browse all Orthopedic devices →